Wintrobe’s Clinical Hematology 14th Edition – John P. Greer

Book Title: Wintrobe’s Clinical Hematology
Book Author: John P. Greer, George M. Rodgers, Bertil Glader, Daniel A. Arber, Robert T. Means, Alan F. List, Frederick R. Appelbaum, Angela Dispenzieri, Todd A. Fehniger
Book Edition: Fourteenth edition
Book Format: EBook
Date published: 2019
Illustrator: Wolters Kluwer.
ISBN: 987654321
Number Of Pages: 7187
Libros de Medicina – Rincón Médico
Wintrobe’s Clinical Hematology
The modern era of hematology, according to Wintrobe, began less than a century ago when the pathogenesis of pernicous anemia was initially described. He outlined the historical perspective in the introduction to his textbook:
When and in what manner blood was first examined is unknown, but before the days of microscopy only the gross appearance of the blood could be studied. Blood allowed to clot in a glass vessel can be seen to form several distinct layers: at the bottom a dark red, almost black, jellylike material is seen; above this is a red layer; and still nearer the top of the clot is a pale green or whitish layer. Above these is the transparent, yellow serum. It has been suggested that perception of these layers in the blood after its removal from the body may have given rise to the doctrine of the four humors (black bile, sanguis, phlegm, and yellow bile), which were believed to constitute the substance of the human body. Health and disease were thought to be the result of the proper mixture or imbalance, respectively, of these four humors. This doctrine corresponding to the pervading concept of matter founded on the interrelationship of the four elements—earth, water, air, and fire—was set out clearly in the Hippocratic writings and was systematized into a complex metaphysical pattern by Galen in the 2nd century AD. It dominated medical thinking even into the 17th century.
CONTENIDO:
- Chapter 1. Examination of the Blood and Bone Marrow
- Chapter 2. Clinical Flow Cytometry
- Chapter 3. Cytogenetics
- Chapter 4. Molecular Diagnosis in Hematology
- Chapter 5. Origin and Development of Blood Cells
- Chapter 6. The Birth, Life, and Death of Red Blood Cells: Erythropoiesis, the Mature Red Blood Cell, and Cell Destruction
- Chapter 7. Neutrophilic Leukocytes
- Chapter 8. The Human Eosinophil
- Chapter 9. Mast Cells and Basophils: Ontogeny, Characteristics, and Functional Diversity
- Chapter 10. Monocytes, Macrophages, and Dendritic Cells
- Chapter 11. Lymphocytes and Lymphatic Organs
- Chapter 12. B Lymphocytes
- Chapter 13. T Lymphocytes
- Chapter 14. Natural Killer and Innate Lymphoid Cells
- Chapter 15. Major Histocompatibility Complex
- Chapter 16. Complement System
- Chapter 17. Megakaryocytes
- Chapter 18. Platelet Structure
- Chapter 19. Platelet Function in Hemostasis and Thrombosis
- Chapter 20. Blood Coagulation and Fibrinolysis
- Chapter 21. Endothelium: Angiogenesis and the Regulation of Hemostasis
- Chapter 22. Red Cell, Platelet, and White Cell Antigens
- Chapter 23. Transfusion Medicine
- Chapter 24. Anemia: General Considerations
- Chapter 25. Iron Deficiency and Related Disorders
- Chapter 26. Sideroblastic Anemias
- Chapter 27. Hemochromatosis
- Chapter 28. Porphyrias
- Chapter 29. Hereditary Spherocytosis,Hereditary Elliptocytosis, and Other Disorders Associated With Abnormalities of the Erythrocyte Membrane
- Chapter 30. Hereditary Hemolytic Anemias Due to RBC Enzyme Disorders
- Chapter 31. Autoimmune Hemolytic Anemia
- Chapter 32. Paroxysmal Nocturnal Hemoglobinuria
- Chapter 33 Acquired Nonimmune Hemolytic Disorders
- Chapter 34. Sickle Cell Anemia and Other Sickling Syndromes
- Chapter 35. Thalassemia Syndromes: Quantitative Disorders of Globin Chain Synthesis
- Chapter 36. Hemoglobins With Altered Oxygen Affinity, Unstable Hemoglobins, M-Hemoglobins, and Dyshemoglobinemias
- Chapter 37. Megaloblastic Anemias: Disorders of Impaired DNA Synthesis
- Chapter 38. Inherited Aplastic Anemia Syndromes Germline
- Chapter 39. Acquired Aplastic Anemia
- Chapter 40. Red Cell Aplasia: Acquired and Congenital Disorders
- Chapter 41. Congenital Dyserythropoietic Anemias
- Chapter 42. Anemias Secondary to Inflammation/Chronic Disease and Systemic Disorders
- Chapter 43. Anemias During Pregnancy and the Postpartum Period
- Chapter 44. Anemias Unique to the Fetus and Neonate
- Chapter 45. Erythrocytosis
- Chapter 46. Diagnostic Approach to the Bleeding Disorders
- Chapter 47. Thrombocytopenia: Pathophysiology and Classification
- Chapter 48. Thrombocytopenia Caused by Immunologic Platelet Destruction
- Chapter 49. Thrombotic Thrombocytopenic Purpura, Hemolytic–Uremic Syndrome, and Related Disorders
- Chapter 50. Miscellaneous Causes of Thrombocytopenia
- Chapter 51. Bleeding Disorders Caused by Vascular Abnormalities
- Chapter 52. Thrombocytosis and Essential Thrombocythemia
- Chapter 53. Qualitative Disorders of Platelet Function
- Chapter 54. Inherited Coagulation Disorders
- Chapter 55. Acquired Coagulation Disorders
- Chapter 56. Thrombosis and Antithrombotic Therapy
- Chapter 57. Diagnostic Approach to Tissue Examination and Testing
- Chapter 58. Neutropenia
- Chapter 59. Qualitative Disorders of Leukocytes
- Chapter 60. Lysosomal Abnormalities of the Monocyte–Macrophage System: Gaucher and Niemann–Pick Diseases
- Chapter 61. Langerhans Cell Histiocytosis
- Chapter 62. Pathology of Langerhans Cell Histiocytosis and Other Histiocytic Proliferations
- Chapter 63. Infectious Mononucleosis and Other Epstein-Barr Virus–Related Disorders
- Chapter 64. Primary Immunodeficiency Diseases
- Chapter 65. Human Immunodeficiency Virus Infection
- Chapter 66. Disorders of the Spleen
- Chapter 67. Tumors of the Spleen
- Chapter 68. Hematopoietic Neoplasms: Principles of Pathologic Diagnosis
- Chapter 69. Principles and Pharmacology of Chemotherapy
- Chapter 70. Supportive Care in Hematologic Malignancies
- Chapter 71. Immunotherapy
- Chapter 72. Gene Therapy for Hematopoietic Stem Cell Disorders
- Chapter 73. Molecular Genetics of Acute Leukemia
- Chapter 74. Diagnosis and Classification of the Acute Leukemias and Myelodysplastic Syndromes
- Chapter 75. Acute Lymphoblastic Leukemia in Adults
- Chapter 76. Acute Myeloid Leukemia in Adults
- Chapter 77. Acute Lymphoblastic Leukemia in Children
- Chapter 78. Acute Myeloid Leukemia in Children
- Chapter 79. Acute Promyelocytic Leukemia
- Chapter 80. The Myelodysplastic Syndromes
- Chapter 81. Pathology of the Myeloproliferative Neoplasms
- Chapter 82. Chronic Myeloid Leukemia
- Chapter 83. Polycythemia Vera
- Chapter 84. Myelofibrosis
- Chapter 85. Eosinophilic Neoplasms and Hypereosinophilic Syndrome
- Chapter 86. Systemic Mastocytosis
- Chapter 87. Diagnosis and Classification of Lymphomas
- Chapter 88. Molecular Genetic Aspects of Non-Hodgkin Lymphomas
- Chapter 89. Non-Hodgkin Lymphoma in Adults
- Chapter 90. Non-Hodgkin Lymphoma in Children
- Chapter 91. Chronic Lymphocytic Leukemia
- Chapter 92. Hairy Cell Leukemia
- Chapter 93. Cutaneous T-cell Lymphoma: Mycosis Fungoides and Sézary Syndrome
- Chapter 94. Hodgkin Lymphoma in Adults
- Chapter 95. Hodgkin Lymphoma in Children
- Chapter 96. Practical Approach to Evaluation of Monoclonal Gammopathies
- Chapter 97. Molecular Genetic Aspects of Plasma Cell Disorders
- Chapter 98. Monoclonal Gammopathy of Undetermined Significance and Smoldering Multiple Myeloma
- Chapter 99. Multiple Myeloma
- Chapter 100. Immunoglobulin Light-Chain (AL) Amyloidosis
- Chapter 101. Waldenström Macroglobulinemia
- Chapter 102. POEMS Syndrome, Cryoglobulinemia, and Heavy-Chain Disease
- Chapter 103. Hematopoietic Cell Transplantation
- Chapter 104. Hematopoietic Cell Transplantation for Nonmalignant Disorders
- Chapter 105. Hematopoietic Cell Transplantation for Hematologic Malignancies
- Chapter 106. Graft-Versus-Host Disease and Graft-Versus-Tumor Response
- Chapter 107. Late Effects After Transplantation