«Biology of Vascular Smooth Muscle Vasoconstriction and Dilatation»
Libros de Medicina en PDF «Biology of Vascular Smooth Muscle: Vasoconstriction and Dilatation» The discovery that the vascular contractility is regulated by a potent diffusible factor derived from the endothelium made by Furchgott and Zawadzki in 1980 is an epoch-making milestone in vascular biology. For a long time, the endothelium has been largely considered as a selective permeable barrier between the circulating blood and the vascular smooth muscle. Intensive studies evoked by Furchgott and Zawadzki’s work since then have firmly established that the endothelium-derived nitric oxide, prostanoids, endothelin, and endothelium-dependent hyperpolarization play a dominant role in the regulation of vascular