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Brody’s Human Pharmacology 6th edition – Lynn Wecker

Book Title: Brody's Human Pharmacology: Mechanism-Based Therapeutics

Book Author: Lynn Wecker, David A. Taylor, Robert J. Theobald Jr.

Book Edition: 6th edition

Book Format: EBook

Date published: 2019

Illustrator: Elsevier

ISBN: 978-0-323-47652-2

Number Of Pages: 2323

Libros de Medicina – Rincón Médico

Brody’s Human Pharmacology: Mechanism-Based Therapeutics

The sixth edition of Brody’s Human Pharmacology has been appropriately subtitled Mechanism-Based Therapeutics and has been designed to provide students in all health professions with pharmacological information and its clinical relevance.
A major goal of this edition has been to present information in the clearest and most concise manner, using prototypical drugs to illustrate basic mechanisms and boxes and tables to emphasize key points and relevant clinical information, with many new figures within each section.
Sections were created with a focus on therapeutics, and two new sections were added to this edition, including one on drug therapy for pain management and another on the treatment of inflammatory, allergic, and immunological disorders. In addition, several new chapters have been added to this edition including:
• A chapter on pharmacogenetics in the Therapeutic Principles Section, critical in this era of personalized medicine
• A chapter on the cannabinoids in the Pain Management Section, particularly important in light of the opioid crisis
• A chapter focused on drugs for the treatment of attention deficit hyperactivity disorder in the Central Nervous System Section, because these medications are being prescribed to an increasing number of children
• A chapter on drug treatment for human immunodeficiency virus and related opportunistic infections in the Chemotherapy Section, because
millions of individuals are dying each year from AIDS-related illnesses.


CONTENIDO:

Section 1: Mechanisms of Drug Action and Therapeutic Principles
  • 1. Introduction
  • 2. Pharmacodynamics
  • 3. Pharmacokinetics
  • 4. Pharmacogenetics
  • 5. Drug Discovery, Development, and Regulation
Section 2: Chemical Mediators and Drugs Affecting Autonomic and Neuromuscular Synapses
  • 6. Introduction to the Autonomic Nervous System
Cholinergic Drugs
  • 7. Muscarinic Agonists, Cholinesterase Inhibitors, and Their ClinicalUses
  • 8. Muscarinic Antagonists and Their Clinical Uses
  • 9. Nicotinic Agonists and Their Clinical Uses
  • 10. Neuromuscular Blocking Drugs and Nicotinic Antagonists
Adrenergic Drugs
  • 11. Adrenergic Agonists and Their Clinical Uses
  • 12. Adrenergic Antagonists and Their Clinical Uses
Section 3: Drug Treatment for Disorders Affecting the Central Nervous System
  • 13. The Central Nervous System
  • 14. Drug Therapy for Alzheimer Disease and Other Cognitive Disorders/Dementias
  • 15. Pharmacotherapy of Basal Ganglia Disorders
  • 16. Drug Therapy for Psychoses and Bipolar Disorder
  • 17. Drug Therapy for Depression and Anxiety
  • 18. Drug Therapy for the Management of Attention Deficit-Hyperactivity Disorder
  • 19. Drug Therapy for Insomnia and the Hypersomnias
  • 20. Drug Therapy for Managing Obesity and Eating Disorders
  • 21. Treatment of Seizure Disorders
  • 22. Drug Therapy for Spasticity Disorders
  • 23. Ethanol, Other Alcohols, and Drugs for Alcohol Use Disorder
  • 24. Illicit Psychoactive Compounds and Substance Use Disorder
Section 4: Drug Therapy for Pain Management
  • 25. Introduction
  • 26. General Anesthetics
  • 27. Local Anesthetics
  • 28. Opioid Analgesics
  • 29. Nonsteroidal Antiinflammatory Agents and Acetaminophen
  • 30. Cannabinoids as Analgesics
Section 5: Treatment of Inflammatory, Allergic and Immunological Disorders
  • 31. Drug Therapy for Migraine Headache
  • 32. Drug Therapy for Gout and Hyperuricemia
  • 33. Drug Treatment for Allergic Reactions
  • 34. Immunosuppressants for Autoimmune Disorders and Organ Transplantation
  • 35. Drug Therapy for Rheumatoid Arthritis
Section 6: Drug Treatment for Cardiovascular Diseases
  • 36. Introduction to the Regulation of Cardiovascular Function
  • 37. Overview of Hypertension
  • 38. Diuretics and Drugs That Affect Volume and
  • 39. Drugs Affecting the Renin-Angiotensin-Aldosterone System
  • 40. Calcium Channel Blockers
  • 41. Vasodilators for Hypertensive Crises, Pulmonary Hypertension, and Erectile Dysfunction
  • 42. Drug Therapy for Hyperlipidemias and Atherosclerotic Cardiovascular Disease
  • 43. Drug Therapy for Myocardial Ischemia and Angina Pectoris
  • 44. Treatment of Heart Failure
  • 45. Antiarrhythmic Drugs
  • 46. Anticoagulant, Fibrinolytic, and Antiplatelet Agents
  • 47. Drug Therapy for Hemophilia and the Deficiency Anemias
Section 7: Endocrine Pharmacology
  • 48. Introduction to Endocrine Pharmacology
  • 49. Treatment of Hypothalamic and Pituitary Disorders
  • 50. Treatment of Adrenocorticosteroid Disorders
  • 51. Female Hormone Regulation
  • 52. Androgens, Antiandrogens, and Their Clinical Uses
  • 53. Drug Therapy for the Management of Diabetes
  • 54. Drug Therapy for the Management of Thyroid Disorders
  • 55. Calcium Regulating Hormones and Other Agents Affecting Bone
Section 8: Chemotherapy
    Infectious Diseases
    • 56. Principles of Antimicrobial Use
    • 57. Drugs Targeting Bacterial Cell Walls and Membranes
    • 58. Drugs Targeting Bacterial Protein Synthesis
    • 59. Drugs Targeting Bacterial DNA
    • 60. Antimycobacterial Agents
    • 61. Drugs Targeting Resistant Organisms
    Parasitic Diseases
    • 62. Antifungal Agents
    • 63. Antimalarial and Other Antiprotozoal Agents
    • 64. Anthelmintics and Ectoparasiticides
    Viruses
    • 65. Antiviral Agents
    • 66. Antiretroviral Drugs for HIV
    Cancer
    • 67. Principles of Antineoplastic Drug Use
    • 68. Cytotoxic Agents
    • 69. Targeted Anticancer Agents
    Section 9: Special Considerations
    • 70. Therapeutic Use of Hematopoietic Growth Factors
    • 71. Gastrointestinal Disorders and Their Treatment
    • 72. Pharmacological Treatment of Asthma and COPD
    • 73. The Role of Nutraceuticals and Natural Products
    • 74. Essentials of Toxicology
    • 75. Therapeutic Considerations for Pregnant, Pediatric, Geriatric,
    • Appendix

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