In the last 40 years, the study of aortic heart valve replacements has had its roots in the
work of great clinicians, scientists and biomedical engineers who established the techniques for heart valve substitutes. Recently, the research on the development of aortic heart valve replacements has shifted toward tissue engineering (TE), a multidisciplinary research that involves biological, biomaterial and bioengineering sciences. This book introduces current valve substitutes and their limitations and the futuristic tissue engineering of aortic heart valves (TEHV).
It highlights the substantial achievements that have been accomplished in the last two decades in TEHV research and discusses the much needed exertion in defining the functional requirements of clinical implementation and in developing the means to produce a functional aortic valve.
Chapter I: Why Tissue Engineering of Heart Valve
Chapter II: Basic Introduction to Heart Valve Diseases
Chapter III: Heart Valve Replacements
Chapter IV: Biomaterials Characterisation
Chapter V: Scaffold Fabrication Techniques
Chapter VI: In Vitro Conditioning— Bioreactors and ECM Generation
Chapter VII: Concept and Development of Tissue Engineering Aortic Heart Valve
Chapter VIII: Closing Remarks and Future Challenges
Title: “TISSUE ENGINEERING OF THE AORTIC HEART VALVE FUNDAMENTALS AND DEVELOPMENTS”
Author: YOSRY S. MORSI