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Pathophysiology: The Biologic Basis For Disease In Adults And Children 8th Edition

Titulo del libro: Pathophysiology: The Biologic Basis For Disease In Adults And Children

Autor del libro: Kathryn L. Mccance, Sue E. Huether, Valentina L. Brashers, Neal S. Rote

Edición de libro: 8th Edition

Formato de libro: EBook

Date published: 2019

Illustrator: Elsevier

ISBN: 978-0-323- 40281-1

Número de páginas: 5816

Descripción

Pathophysiology
Pathophysiology incorporates basic, translational, and clinical research to advance understandings of disease and dysfunction. The study of pathophysiology involves many biomedical sciences and a wide range of research activities. Multiple aspects of cellular physiology are progressing rapidly, generating vast amounts of data to understand. The information expansion involves a greater understanding of the behavior of individual cells, their neighboring microenvironment, and the molecules that not only make up those cells but also communicate with their surroundings. Importantly, the forward movement of biomedical sciences occurs within the context of social, economic, and political processes that determine how disease is defined, experienced, and treated.
Interdisciplinary research has led to significant advancements in genetics, epigenetics, cell signaling and communication, control of cell behavior, metabolism, and cell fate. Knowledge about normal cell structures, function, and signaling pathways is at the forefront of translational science and foundational to the understanding of pathophysiology. Cells are nimble and respond to changes in their environment. Advancements in tools to observe cells are providing new understanding of cellular processes, including how cells function and prioritize their activities, monitor their environment, move, differentiate, and regenerate. For disease, conditions of cells under stress—for example, when stem cells become corrupted—help to define restorative activities that are lost. An important emerging goal is to learn what biologic switches restore function and reprogram the cell for normal function.

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CONTENIDO:

Part 1: CENTRAL CONCEPTS OF PATHOPHYSIOLOGY: CELLS AND TISSUES
  • Unit I: THE CELL
  • 1. Cellular Biology
  • 2. Altered Cellular and Tissue Biology: Environmental Agents
  • 3. The Cellular Environment: Fluids and Electrolytes, Acids and Bases
Unit II: GENES AND GENE-ENVIRONMENT INTERACTION
  • 4. Genes and Genetic Diseases
  • 5. Genes, Environment-Lifestyle, and Common Diseases
  • 6. Epigenetics and Disease
Unit III: MECHANISMS OF SELF-DEFENSE
  • 7. Innate Immunity: Inflammation
  • 8. Adaptive Immunity
  • 9. Alterations in Immunity and Inflammation
  • 10. Infection
  • 11. Stress and Disease
Unit IV. CELLULAR PROLIFERATION: CANCER
  • 12. Cancer Biology
  • 13. Cancer Epidemiology
  • 14. Cancer in Children
Part 2: PATHOPHYSIOLOGIC ALTERATIONS: ORGANS AND SYSTEMS Unit V: THE NEUROLOGIC SYSTEM
  • 15. Structure and Function of the Neurologic System
  • 16. Pain, Temperature Regulation, Sleep, and Sensory Function
  • 17. Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function
  • 18. Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction
  • 19. Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders
  • 20. Alterations of Neurologic Function in Children
Unit VI: THE ENDOCRINE SYSTEM
  • 21. Mechanisms of Hormonal Regulation
  • 22. Alterations of Hormonal Regulation
  • 23. Obesity and Disorders of Nutrition NEW
Unit VII: THE REPRODUCTIVE SYSTEMS
  • 24. Structure and Function of the Reproductive Systems
  • 25. Alterations of the Female Reproductive System
  • 26. Alterations of the Male Reproductive System
  • 27. Sexually Transmitted Infections
Unit VIII: THE HEMATOLOGIC SYSTEM
  • 28. Structure and Function of the Hematologic System
  • 29. Alterations of Erythrocyte, Platelet, and Hemostatic Function
  • 30. Alterations of Leukocyte and Lymphoid Function
  • 31. Alterations of Hematologic Function in Children
Unit IX: THE CARDIOVASCULAR AND LYMPHATIC SYSTEMS
  • 32. Structure and Function of the Cardiovascular and Lymphatic Systems
  • 33. Alterations of Cardiovascular Function
  • 34. Alterations of Cardiovascular Function in Children
Unit X: THE PULMONARY SYSTEM
  • 35. Structure and Function of the Pulmonary System
  • 36. Alterations of Pulmonary Function
  • 37. Alterations of Pulmonary Function in Children
Unit XI: THE RENAL AND UROLOGIC SYSTEMS
  • 38. Structure and Function of the Renal and Urologic Systems
  • 39. Alterations of Renal and Urinary Function
  • 40. Alterations of Renal and Urinary Tract Function in Children
Unit XII: THE DIGESTIVE SYSTEM
  • 41. Structure and Function of the Digestive System
  • 42. Alterations of Digestive Function
  • 43. Alterations of Digestive Function in Children
Unit XIII: THE MUSCULOSKELETAL SYSTEM
  • 44. Structure and Function of the Musculoskeletal System
  • 45. Alterations of Musculoskeletal Function
  • 46. Alterations of Musculoskeletal Function in Children
Unit XIV: THE INTEGUMENTARY SYSTEM
  • 47. Structure, Function, and Disorders of the Integument
  • 48. Alterations of the Integument in Children
Unit XV: MULTIPLE INTERACTING SYSTEMS
  • 49. Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults
  • 50. Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children
Anatomia Biologia Cardiologia Cirugia Enfermeria Farmacología Fisiología Ginecología Odontologia Oncología Otros Pediatría Psicología
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